JD Supra

FDA Issues Guidance on Modernizing Statistical Methods for Clinical Trials

In a new draft guidance issued on January 14, 2026, the FDA discussed the use of a modern statistical methodology in clinical trials designed to ...

BioStem Technologies Highlights Alignment with FDA’s Openness to Bayesian Statistical Approaches in Clinical Research

BioStem remains committed to advancing evidence-based innovation in wound care through rigorous clinical research and real-world data analysis, supported by its proprietary BioRetain ® process and ...
Nature

Longitudinal Data Analysis and Bayesian Modeling

Longitudinal data analysis is an essential statistical approach for studying phenomena observed repeatedly over time, allowing researchers to explore both within-subject and between-subject variations ...
The BMJ

FDA is now “open to bayesian statistics”: transformational change or new Pandora’s box?

The US Food and Drug Administration (FDA) is now “open to bayesian statistics,” contrasting this with the frequentist approach that the agency and the drug industry have historically relied on for ...
JSTOR Daily

Bayesian Analysis of Proportional Hazards Models Built from Monotone Functions

We consider the usual proportional hazards model in the case where the baseline hazard, the covariate link, and the covariate coefficients are all unknown. Both the baseline hazard and the covariate ...
JSTOR Daily

Multivariate Fay–Herriot Bayesian estimation of small area means under functional measurement error

Journal of the Royal Statistical Society. Series A (Statistics in Society), Vol. 180, No. 4 (OCTOBER 2017), pp. 1191-1209 (19 pages) Area level models, such as the Fay–Herriot model, aim to improve ...
TCTMD

New EXCEL Analysis Reignites Debate Over PCI for Left Main CAD

(UPDATED) A statistical deep dive into the EXCEL trial, one that also includes evidence from other revascularization studies in the setting of left main coronary artery disease, shows that there is ...