A recent article in Small highlights a new method for studying tumor cell interactions and testing anti-metastatic drugs through the development of an Under-oil Open Microfluidic System (UOMS). This ...

Researchers headed by a team at NYU Langone Health have discovered that a feature of pancreatic cancer cells’ surroundings determines whether they grow fast or become resistant to chemotherapy. The ...

CAFs Impact ECM and tumor growth: CAFs secrete MMPs to degrade ECM, releasing growth factors for cancer cells. ECM changes counteract CAFs and tumor cells: (a) Hard ECM triggers Twist release from ...

Cell migration is a multistep process essential to various physiological functions, including immune cell movement and embryonic development, as well as pathological conditions like tumor metastasis.

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...