Breast cancer development is not solely the result of cancer cells acting independently, it involves a dynamic and complex ecosystem composed of cancer cells, immune cells, fibroblasts, adipocytes, ...

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

A metabolic enzyme found in the support cells surrounding tumors may hold the key to predicting which cancer patients will ...

A new metabolic mechanism describes how tumors disable “gatekeeper” cells to prevent immune response to cancer.

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the ...

Tumor growth unfolds within a tumor microenvironment (TME) defined by metabolic–immune crosstalk. Emerging evidence indicates that cancer cells not only reprogram glycolysis but also alter amino acid, ...

In this study, a principle of cancer cell metabolism was elucidated by integrating 13 C-metabolic flux analysis with flux balance analysis. The findings reveal that glycolysis-dependent, less ...

A research team led by Purdue University's W. Andy Tao has discovered a new type of protein modification related to cellular ...

Up to 80 percent of patients with cancer struggle with cachexia, often called wasting syndrome, which is a condition characterized by the inability to gain or maintain body weight. One of the reasons ...

Hyeyoung Nam, Ph.D., professor in the UAB Department of Urology, has been published in Science Advances alongside corresponding author, Sunil Sudarshan, M.D. and colleagues Richard L. Kirkman and ...