Scientists at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences have developed a multi-chamber organoid that mirrors the heart’s intricate structure. The human ...
In humans, a specialized mRNA translation circuit predetermines the competence for heart formation at an early stage of embryonic development, a research team at the Center for Molecular Medicine ...
Scientists have created a three-dimensional "heart-on-a-chip" (HOC) model that beats on its own, uses calcium to initiate ...
Mechanical cues are key regulators of cardiac development, yet their role in organoid maturation remains underexplored. In a new study, researchers introduce a magnetic torque stimulation (MTS) system ...
In the left part can be seen multi-omics analysis suggested some proteins (histone / non-histone), protein lactylation, and genes change significantly at different developmental stages (1 w [week], 6 ...
A University of Houston pharmacology researcher and expert in cardiac development has identified a new cause of—and repair for—left ventricular non-compaction, also known as spongy heart disease. The ...
Heart disease remains the leading cause of death worldwide, yet progress in understanding and treating cardiac disorders is limited by the shortcomings of existing experimental models. Traditional ...