By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...

A simulated cell in the early stages of division. Left half shows membrane (green cubes), and ribosomes (yellow/purple) interwoven through in the cell’s chromosome (red). Right side shows all the ...

One of the holy grails of biology is digitally simulating a living cell. If researchers can use computers to more accurately understand how new medicines would react in the body, that could give them ...

Drug discovery requires experimental systems that more accurately capture the complexity of human tissues. However, animal models and conventional cell culture approaches often lack the physiological ...

A human cell is a Rube Goldberg machine like no other, full of biological chain reactions that make the difference between life and death. Understanding these delicate relationships and how they go ...

A vascularized organoid model of hormone-secreting cells in the pancreas has been developed, with potential to improve diabetes research and cell-based therapies. “Our results highlight the importance ...

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...