Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that ...

Scientists have uncovered an unexpected mechanism by which the gut’s immune system maintains balance, challenging ...

Complement Factor H (CFH) is a pivotal regulator of the complement system, integral to maintaining immune homeostasis and protecting host tissues from undue complement‐mediated damage. By inhibiting ...

Calorie restriction lowers C3, an immune protein tied to aging and inflammation, improving health without requiring weight ...

The story of Q32 Bio, a company that develops therapeutics for inflammatory and autoimmune diseases, started two decades ago. That's when V. Michael Holers, MD, a University of Colorado School of ...

Artificial intelligence is increasingly being used to help scientists accelerate drug discovery and search for new treatments.

Cedars-Sinai investigators have identified a genetic variant that increases people's risk of developing perianal Crohn's disease, the most debilitating manifestation of Crohn's disease. Science X ...

Ocular infections and related inflammatory disorders are important causes of visual morbidity worldwide and may arise from viral, bacterial, fungal, and ...

Each year, six Nobel Prizes are awarded in the fields of physiology or medicine, physics, chemistry, economics, literature and peace work. This year, the Nobel Prize in Physiology or Medicine was ...