Researchers at the Medical University of Vienna and the Medical University of Innsbruck discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement ...

Figure 1: Mannose-binding lectin (blue strands) can bind to sites on the SARS-Cov-2 spike protein on the cell membrane. One of the most striking features of the SARS-CoV-2 pandemic is that across all ...

This is a preview. Log in through your library . Abstract Rabbits sensitized by multiple injections of living BCG until their serums showed high concentrations of antibodies to tuberculoprotein and ...

- Proprietary tissue-targeted complement platform and best-in-class IL-7R antibody technology to treat patients with severe autoimmune and inflammatory disease; clinical trials begin in 2020 ...

Herpes viruses enter the body and hide away in cells, often re-emerging later to cause illnesses such as shingles, genital herpes and cancer. How these viruses evade the immune system remains poorly ...

The complement component C5a and its receptors, C5aR1 and C5aR2, are central to the orchestration of innate immunity. C5a is a potent anaphylatoxin generated during complement activation, acting as a ...

In a recent study published in The New England Journal of Medicine, researchers reviewed selected acute-phase proteins concerning their production, structure, and function. The advent of severe acute ...

New Burnet Institute research has revealed the importance of specific proteins in the blood known as complement to clear infection and prevent malaria in pregnancy, a cause of severe disease and ...