GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...

This article explains how diet creates sustained epigenetic changes that affect long-term health, disease risk, aging, and ...

A team led by Professor Shoichiro Asayama at Tokyo Metropolitan University has synthesized a charge-free molecule designed to sneak plasmid DNA into living cells via hydrogen bonding, dramatically ...

The first cell rejuvenation therapy is set to enter clinics, testing if aging cells can be reset to a younger, healthier ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

Cars patched up after a wreck may look fixed—but never run quite as before. The same may hold true for chromatin, according to a study published in Science on November 6. In response to double-strand ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

Scientists have developed an AI system that analyzes complex gene-expression signatures to estimate the likelihood that a tumor will spread.

Human metabolism is regulated by internal clocks, the so-called circadian rhythms. Many processes, such as sugar uptake, fat ...