Results of seasonal analyses showed that SU levels and flare frequency followed a similar pattern across the year, with higher values in late spring and summer. Mean SU levels were highest from April ...

The study describes the variations of gout flares and assesses the different methods of gout flare reporting in clinical trials. Among patients with gout, the wide variation of flare patterns presents ...

Phase II prospective trial of cetuximab and radiotherapy for locally advanced, squamous cell carcinomas of the head and neck in patients >70 years old or with comorbidities not-eligible for ...

First in human phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of KU-0059436 (Ku), a small molecule inhibitor of poly ADP-ribose polymerase (PARP) in cancer patients (p), including BRCA1/2 ...