Many cancers are caused by fusion oncoproteins, molecules that aberrantly form when a rearrangement of DNA results in parts of two different proteins being expressed as one. Several fusion ...

There has been a missing puzzle piece in phase separation and its role in cancer. Now, researchers at the University of North Carolina (UNC) at Chapel Hill and the UNC Lineberger Comprehensive Cancer ...

Researchers have discovered the key role of the extracellular environment in dictating the ability of mutated cells to induce cancer formation. To form a cancer, cells need to accumulate oncogenic ...

The mechanism by which breast cancer is formed in the cells of mammalian epithelium has been discovered. Although roughly 20 mutations accumulate annually in each epithelial cell until menopause, the ...

A study published in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilize the cancer genome. Unstable genomes are a fertile playground for cancer ...

The team is led by Leanne Li of The Francis Crick Institute in London, England. Her research combines cancer biology and neuroscience to investigate how cancer communicates with peripheral nerves ...

Blood clots form in response to signals from the lungs of cancer patients—not from other organ sites, as previously thought—according to a preclinical study by Weill Cornell Medicine, Memorial Sloan ...

Gastric cancer ranks among the leading malignant tumors worldwide in both incidence and mortality. Its early symptoms are often atypical, and diagnosis frequently occurs at advanced stages, resulting ...