Peroxiredoxins are among the most abundant enzymes involved in managing oxidative stress. They control the levels of peroxides such as hydrogen peroxide, relay redox signals, and help protect other ...
In response to stimulation, young cells produce H2O2 and transduce signals through a PRDX2-based redox relay, thereby activating RRC. However, in senescent cells, the increase in PRDX2 hyperoxidation ...