A new model of the cellular response to plasma membrane damage. Within ~2 minutes of damage, Pkc1 proteins flood to the damage site to stabilize the puncture, and other proteins involved in the growth ...

Membrane proteins are ubiquitous cellular components that are responsible for a wide array of cellular and molecular activities, including drug metabolism, lipid shuttling, and antibiotic resistance.

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

Study shows how viral single-gene lysis proteins lock the peptidoglycan flippase MurJ into an outward-facing state ...

Membrane proteins are key targets for therapeutic intervention using antibody biologics. Over 60% of FDA-approved drugs act on these proteins. Studying them is challenging because the proteins must be ...

A recent study by the University of Bonn and University Hospital Bonn and the University of Freiburg shows that the ...

A surprising new function of essential hearing proteins may explain why some genetic mutations and common antibiotics lead to permanent deafness.

Edward Lyman, associate professor in the departments of physics and astronomy, as well as chemistry and biochemistry, was recently published in the journal Nature Chemical Biology. The article, “When ...