The creation of a woolly-mouse embryo marks a significant leap in the field of de-extinction, bringing us one step closer to reviving the iconic woolly mammoth. By combining advanced gene-editing ...
Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...
It’s challenging to sustain a pregnancy when food is short, or conditions are otherwise tough. That’s why many mammalian embryos can postpone their growth to get through periods of environmental ...
A stretch of DNA in the mouse genome left by ancient viral infections is crucial for early development in the womb, new research shows. According to the study, published in December in the journal ...