Mutational Analysis of Patients With Colorectal Cancer in CALGB/SWOG 80405 Identifies New Roles of Microsatellite Instability and Tumor Mutational Burden for Patient Outcome Comparative efficacy ...

Observational research is core to drug development, helping researchers understand the natural history of diseases and the real-world impact of treatments on patients. Observational studies frequently ...

• Accounting for bias is a major challenge confronting the use of observational data to gain important insights into real-world treatment effects. • No single study design will satisfy all information ...

ABOUT THE AUTHORS: RACHAEL L. FLEURENCE, HUSEYIN NACI & JEROEN P. JANSEN Rachael Fleurence, Huseyin Naci, and Jeroen Jansen team up in this issue of Health Affairs to make the case that observational ...

Since its introduction, the AI-powered chatbot ChatGPT has made waves across the education sector. Just one of many generative AI programs, the web-based tool has the ability to create comprehensive ...

A study comparing different statistical methods used to remove the effects of selection bias in observational studies finds that results may vary and caution may be warranted when interpreting ...

Statisticians point out that medical and other observational studies often produce results that are later shown to be incorrect. They now suggest ways to fix the system. S. Stanley Young, assistant ...

Would you volunteer to become vegetarian for the next three decades for the sake of science? What if you were asked to run at least 50 kilometres per week, or live through a natural disaster? Granted, ...