Observational analyses can complement randomized clinical trial findings for the study of HPV vaccine effectiveness

Led by researchers at NDORMS as part of the Data Analysis and Real World Interrogation Network (DARWIN EU) initiative, a new ...
National Academies of Sciences%2c Engineering%2c and Medicine

Observational Studies in a Learning Health System: Workshop Summary

• The choice between an observational study and a randomized controlled trial (RCT) is not binary. • No algorithm exists for determining whether an observational study or an RCT is best for answering ...
ascopubs.org

Comparative Effectiveness Research in Oncology Methodology: Observational Data

The goal of comparative effectiveness research is to inform clinical decisions between alternate treatment strategies using data that reflect real patient populations and real-world clinical scenarios ...
Kaleido Scope

CREST-2 Long-term Observational Extension Study (C2LOE)

CREST-2 (clinicaltrials.gov number: NCT02089217) is a pair of parallel, actively recruiting procedural trials to prevent stroke comparing: 1) carotid endarterectomy (CEA) and intensive medical ...
ascopubs.org

Extending the OMOP Common Data Model and Standardized Vocabularies to Support Observational Cancer Research

The OMOP Oncology Module provides a platform for standardization of cancer data enabling the conduct of observational cancer studies and identifying patient cohorts in a distributed research network.