Manual patch clamping requires considerable skill and experience due to the technically challenging setup requirements, and as such, only allows recording of a small sample of cells (approximately ...

To obtain electrophysiological recordings in brain slices, sophisticated and expensive pieces of equipment can be used. However, costly microscope equipment with infrared differential interference ...

Patch–clamp electrophysiology has been an invaluable technique in neuroscience; patch–clamp recordings from whole cells can provide a detailed picture of the electrophysiological properties of neurons ...