Animals such as spiders make fibers which are strong and elastic. These fibers have a polypeptide structure and serve as inspiration for research into the development of functional materials.
A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides. 1 This ...
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New technique synthesizes non-natural amino acids for advanced peptide therapeutics
Ozempic has been making headlines for its remarkable success in treating obesity and diabetes. Yet it is just one in a rapidly growing class of drugs called peptide therapeutics that sits between ...
Advancements in peptide and oligonucleotide synthesis via precision chemistry are transforming therapeutic development by enabling improved scalability and purity.
Chemoenzymatic synthesis represents an innovative fusion of chemical and enzymatic methodologies to orchestrate the assembly of peptides and polymers under mild, environmentally benign conditions. By ...
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