Schematic representation of axonal transport vesicles (blue) carrying presynaptic proteins (SV and AZ proteins). Kinesin motor proteins (KIF1A) attach these vesicles and carry them along the axons to ...
A new study has revealed how tau – a microtubule-binding protein that is implicated in Alzheimer’s disease – weakens transmission across synapses in the brains of mice When injected into presynaptic ...
A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction and memory loss in Alzheimer’s disease. A tool, developed in the Tracy lab ...
The human brain contains nearly 86 billion neurons, constantly exchanging messages like an immense social media network, but neurons do not work alone – glial cells, neurotransmitters, receptors, and ...