Escherichia coli remains at the forefront of recombinant protein production, owing to its rapid growth, well-characterised genetics and the ease with which it can be genetically manipulated. The ...
Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...
This article and associated images are based on a poster originally authored by Marina Fedorova and Ian Hiles and presented at ELRIG Drug Discovery 2024 in affiliation with GSK. This poster is being ...
The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...
GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...
The Expi293™ PRO Expression System is a high-performance transient HEK293 mammalian protein expression platform designed to help researchers express more proteins faster, at higher yields, and with ...
Impact of lorlatinib dose modifications on adverse event outcomes in the phase 3 CROWN study. RC108 in combination with furmonertinib in patients with locally advanced or metastatic EGFR-mutated ...
To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...
As key molecules on the surface of immune cells, Fc receptors are the core hub of antibody-mediated effector functions. They play an irreplaceable role in physiological processes such as ...
Gene therapy has been successfully used to treat a number of diseases, including immune deficiencies, hereditary blindness, ...
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