SELEX (Systematic Evolution of Ligands by EXponential enrichment) was first described and used in 1990 to isolate a functional oligonucleotide from a random pool of differently-shaped DNA or RNA ...
* if the sequences were made periodic, no sequence would be a time shifted version of another sequence * oscillating sequences are not allowed (no 10101010..., no 11001100..., etc) The first and the ...
In the real world, probability is a tough thing to characterize. If I roll a die, what does it mean to say that it has a one-sixth chance of coming up 5? We say that the outcome is random because we ...
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