A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, ...

Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

This Research Topic is the second volume of the “Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics” ...

Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...