Research is shaking up how we think about evolution, suggesting there's a level of predictability influenced by genes and genetic history.

A Mendelian randomization study reveals PCSK9 inhibitors may reduce low back pain (LBP) risk, while HMGCR and NPC1L1 inhibitors show no significant association, providing genetic evidence for ...

This study explores the relationship between gallstones, cholecystectomy, and cancer risk through both observational and Mendelian randomization (MR) methods. The research aims to clarify the ...

Mezigdomide (a CELMoD) combined with carfilzomib/dexamethasone met the phase 3 primary endpoint, delivering statistically ...

Pharmacogenetic testing, which is used to classify how patients with major depressive disorder (MDD) metabolize medications, reduces adverse drug-gene interactions, new research shows. In a randomized ...

A Multicenter Open-Label Randomized Phase II Study of Osimertinib With and Without Ramucirumab in Tyrosine Kinase Inhibitor–Naïve EGFR-Mutant Metastatic Non–Small Cell Lung Cancer (RAMOSE trial) The ...

The same BMI criteria were used to determine eligibility for study randomization. Any individual who completed the run-in phase but did not fulfill the BMI randomization criteria was considered ...

AI risk findings highlight chaotic failures over goal-driven behavior; majority voting and rollback cut variance by aggregating multiple outputs.