Susanna Sova studying a pig molar cusp that was modelled in the study. Credit: Jukka Jernvall The tooth is the most mineralized tissue in the mammalian body and holds information about the creature it ...

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to ...

Scientists have looked our ancestors in the mouth and extracted a new insight about human evolution. Slowed-down tooth growth, a marker of extended childhood development in humans, emerged by only ...

Two distinct stem cell lineages that drive tooth root and alveolar bone formation have been identified by researchers from Science Tokyo. Using genetically modified mice and lineage-tracing techniques ...

A hypothetical model illustrating how reduced Hedgehog signaling alters interactions between the rudimentary tooth bud (R2) and the first molar (M1), leading to supernumerary (SN) tooth or molar ...

Most reptiles and fish have multiple sets of teeth during their lifetime. However, most mammals, such as humans, have only one set of replacement teeth and some mammals, like mice, have only a single ...