Cytokines are a large group of bioactive small molecule proteins synthesized and secreted by immune and non-immune cells. There are various types of cytokines that belong to different families and ...

Microglial cells, the primary immune cells of the brain and central nervous system, are known to undergo striking morphological changes in response to sensory or neural stimuli. However, the ...

Psoriasis, a chronic inflammatory skin condition characterized by dry and scaly skin lesions, affects about 7.5 million people in the United States. Psoriasis results from abnormal proliferation of ...

CD4+ T cells, or helper T cells, are one type of lymphocyte that helps coordinate the immune response against infection and disease. They interact and activate other cells in the immune system. The ...

Structural equivalence is demonstrated through the comparison of a synthetic multinuclear metal complex (left) versus the designer enzyme in this report (right). A collaborative research team led by ...

Cytokines play a central role in regulating physiological processes, largely because of their ability to orchestrate intercellular communication. As ...

Studies have demonstrated a critical role of the cytokines thymic stromal lymphopoietin (TSLP), IL-33, and IL-25, produced by epithelial and other cells at mucosal surfaces in response to a wide range ...

FHAB platform is the foundation of a modular, plug-and-play construct for potentiating a range of large molecule therapeutic classes, including cytokines, peptides, antibodies and vaccines. Sonnet’s ...

A collaborative research team has successfully developed designer enzymes that exhibit both intrinsic and extrinsic functions by transplanting a synthetic trinuclear zinc center into a human cytokine.