Why do diabetic wounds refuse to heal? A new scientific review highlights how disruptions in the timing and behavior of ...

This work was supported by NIH grants to DK Agrawal. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial ...

Chronic diabetic ulcers represent one of the most challenging complications in modern healthcare, affecting over 131 million people worldwide and generating approximately $755 billion in annual ...

Indiana University School of Medicine researchers have made significant progress in understanding how cells communicate during inflammation. The study, recently published in PNAS, was conducted over a ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or “tolerate” molecules found on ...

Mycobacterium tuberculosis, the pathogen responsible for tuberculosis, has evolved a remarkably layered set of molecular ...

CD123 is universally and highly expressed on BPDCN cells. Because CD123 expression is significantly lower on normal hematopoietic stem cells, it provides a distinct "therapeutic window," allowing for ...