Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

The authors review developments in wet granulation using a twin-screw extruder. As a result of changing philosophies towards continuous manufacturing, new equipment is being introduced into ...

Pharmaceutical research and development (R&D) and industry require a continuous fluid-bed dryer that provides a lengthy process time and delivers a high standard for a long time. This article ...

We try to use previous experience to develop the optimal granulation process for each new ingredient, but we sometimes get it wrong. Many times, we?ve taken materials from the granulator only to find ...

Granulation is a critical unit operation in pharmaceutical manufacturing, where fine powders are agglomerated into granules to improve flow properties, uniformity, and compaction performance. The ...

Granulation processes are used for converting light fine powders into large, dense granules to make fast-dissolving drinks, optimized blends for compression tableting, and granules for waste water ...

Continuous processing as described by the regulatory agencies is the pharmaceutical industry’s area of focus in order to enhance product quality and productivity. It is essential to understand the ...

The 11th International Granulation Course, organised by the Sheffield Particle Product Group, was recently held at The University of Sheffield. This event highlighted the University's ongoing ...