Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

The story of life’s beginnings gets stranger when you look closely at viruses. These tiny entities seem to sit at the edge of ...

A giant DNA virus pulled from a Japanese freshwater pond is forcing scientists to rethink how complex cells first acquired their defining feature: the nucleus. Named ushikuvirus, the newly ...

Researchers in Japan have identified a striking new way immune cells strip DNA out of dying neighbors, a process they call ...

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily. So for ...

Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...

Scientists have recently been learning more about the importance of small bits of circular genetic material known as extrachromosomal DNA (ecDNA). These little circles of DNA can hitch a ride with ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by researchers at Goethe University Frankfurt, part of the Rhine-Main University ...

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...

Cells were long believed to safeguard nuclear contents, releasing them only during cell death. Extracellular DNA was thought ...