Scientists from Japan have developed a new technique for assessing whether adeno-associated virus (AAV) capsids are full or empty of their therapeutic DNA payload. The team hopes the research will ...
Combining a plaque-binding fluorescent dye with flat and tapered optical fibers enables depth-resolved monitoring across brain regions during natural behavior, offering a minimally invasive way to ...
If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in ...
At the University of Oxford, Justin Benesch studies assemblies made between proteins called molecular chaperones and the proteins they protect in cells. These assemblies slow the formation of amyloid ...
If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in ...
The presence of inactive, empty capsids in potentially large quantities is one of the main challenges in AAV production. Quantifying the ratio of empty-full AAV capsids is currently ...
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