This article demonstrates how much material can be loaded on a Preparative Thin Layer Chromatographic Plate. Determining how much material should be loaded requires consideration of how much adsorbent ...
After Anna Poryvai tried purifying her reaction product using preparative thin-layer chromatography (prep-TLC), her silica plate ended up looking like an impressionist’s attempt at painting daybreak.
Anna Poryvai, a postdoc at the Swiss Federal Institute of Technology (EPFL), suggested that a student in her lab synthesize a fluorescent dye intermediate. To purify the intermediate, the student ...