Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

The books Lies, Damn Lies, and Statistics (Wheeler, 1976) and Damned Lies and Statistics (Best, 2001) have raised questions about whether statistics can be trusted. A number of educated people today, ...

The advent of technologies to probe DNA copy number genome-wide has led to rapid progress in the understanding of how segments of the genome can vary in copy number between individuals 1,2. In ...

Statistical significance is a critical concept in data analysis and research. In essence, it’s a measure that allows researchers to assess whether the results of an experiment or study are due to ...

A test of statistical significance addresses the question, How likely is a result, assuming the null hypotheses to be true. Randomness, a central assumption underlying commonly used tests of ...

Misuse of statistics in medical and sports science research is common and may lead to detrimental consequences to healthcare. Many authors, editors and peer reviewers of medical papers will not have ...

This is a preview. Log in through your library . Abstract A nonparametric statistical test of the performance of ordinations is adapted and extended from the work of Feigin and Cohen (1978). Two ...

Statistics is to science as steroids are to baseball. Addictive poison. But at least baseball has attempted to remedy the problem. Science remains mostly in denial. True, not all uses of statistics in ...