Scientists are uncovering the intricate shapes and processes of DNA that go far beyond the textbook double helix. From visualizing tangled structures with nanometer precision to decoding how cells ...

DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

SIRF, a method that maps reversed DNA replication forks in single cells, uncovering epigenetic signals linked to replication ...

DNA is more than just the iconic double helix we learned in school—it's a dynamic, complex structure at the heart of life. From high-speed replication to advanced sequencing technologies, scientists ...

DNA replication is a tightly controlled process that copies the genetic code, allowing its instructions to be conveyed from one generation of cells to the next. In diseases like cancer, these ...

Shixin Liu is pioneering new ways of studying the tiny proteins that copy and read DNA in living cells. (Credit: Roshni ...