The nonsteroidal mineralocorticoid receptor antagonist finerenone has been reported to improve kidney and cardiovascular outcomes in persons with type 2 diabetes and chronic kidney disease (CKD).

Background Patients with heart failure (HF) frequently suffer from undetected declines in cardiorespiratory fitness (CRF), which significantly increases their risk of poor outcomes. However, current ...

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Panel A shows a cross-section of a normal heart (top) and an endomyocardial biopsy sample from a normal heart (bottom; with hematoxylin and eosin staining) that shows normal histologic characteristics ...

Background: A limited number of studies have examined the prognostic significance of diastolic function in patients with preserved left ventricular ejection fraction (LVEF) in a general population ...

Our female subjects were slightly older than the male subjects (72.8 ± 7 vs. 67.4 ± 3.3 years of age, p = 0.002) ( Table II). One half of our male subjects had normal diastolic function, whereas mild ...

Mohamed Lamine Tegui Camara, Soriba Bangoura, Aly Traore, Moussa Traore, Kadiatou Mamadou Bobo Barry, Amadou Yaya Diallo, Fousseny Diakite, Mohamed Lamine Kaba Donka Nephrology and Haemodialysis ...

People who have early signs of heart problems may also have changes in brain health that can be early signs of dementia, such as loss of brain volume, according to a meta-analysis published on March ...

Muscle proteins of the obscurin protein family play important roles in sarcomere organization and sarcoplasmic reticulum and T-tubule architecture and function. However, their precise molecular ...

This systematic literature review and pooled rates analysis investigated the standard of care for patients with heart failure in the US post hospital discharge. Results: There were 31 studies that met ...

Cardiomyopathy is the leading cause of mortality in patients with DMD. Compared with their healthy counterparts, patients with DMD — including those with preserved left ventricular ejection fraction ...