Super Bowl squares have become an American tradition nearly on par with the big game itself. But how do they work?

The saying “round pegs do not fit square holes” persists because it captures a deep engineering reality: inefficiency most ...

Figure 1: Maleimido-QA compounds as tethered blockers. Figure 2: Effect of 21 Å tethered QAs on Shaker K + channels. Figure 4: Single-channel block by a 32 Å maleimido-QA. The approach introduced in ...