Open Heart

Enhanced cardiovascular disease risk prediction using integrated machine learning models: a study from the UK Biobank cohort

Objective Cardiovascular diseases (CVD) remain the leading cause of mortality globally, necessitating early risk ...
BMJ

Association between heavy alcohol consumption and cryptogenic ischaemic stroke in young adults: a case–control study

Background The underlying risk factors for young-onset cryptogenic ischaemic stroke (CIS) remain unclear. This multicentre study aimed to explore the association between heavy alcohol consumption and ...
BMJ

Central nervous system tumours and occupational ionising radiation exposure: a nested case–control study among the ORICAMs cohort of healthcare workers in France

Objective This study aimed at investigating the relationship between occupational exposure to external ionising radiation and central nervous system (CNS) tumours mortality in healthcare workers ...
BMJ

Prevalence and risk of adverse intrapartum-related outcomes in Uganda: a cross-sectional study with nested case–control

Introduction Intrapartum-related complications are a leading cause of adverse perinatal outcomes, including stillbirths, neonatal deaths and intrapartum-related neonatal encephalopathy (IP-NE). We ...
ahajournals.org

Recurrent Ischemic Stroke and Vaginal Estradiol in Women With Prior Ischemic Stroke: A Nationwide Nested Case-Control Study

Systemic estrogen replacement therapy is contraindicated in women with a history of ischemic stroke due to the risk of stroke recurrence. There are currently no published data available describing the ...
The Lancet

Discontinuation of menopausal hormone therapy and risk of fracture: nested case–control studies using routinely collected primary care data

Copyright: © 2025 The Author(s). Published by Elsevier Ltd. Women benefit from reduced fracture risk while using menopausal hormone therapy. However, information on ...
Frontiers

Intestinal microbiota changes in early life of very preterm infants with bronchopulmonary dysplasia: a nested case–control study

1 Department of Pediatrics, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China 2 Department of Pediatrics, The Affiliated Suqian Hospital of Xuzhou Medical University, ...
C&EN

The Potential Carcinogenicity of Long-Term Polymetallic Exposure on the Development of Primary Liver Cancer: Nested Case-Control Evidence from the Jinchang Cohort Study

Department of Medical Records, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu, P. R. China Department of Epidemiology and Health Statistics, School of Public Health, Lanzhou ...
The Lancet

Pathogen-specific host response in critically ill patients with blood stream infections: a nested case–control study

aCentre for Infection and Molecular Medicine, Amsterdam University Medical Centre, Location Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands bAmsterdam Institute for ...
Scientific Research Publishing

Bijker, J.B., Persoon, S., Peelen, L.M., Moons, K.G.M., Kalkman, C.J., Kappelle, L.J., et al. (2012) Intraoperative Hypotension and Perioperative Ischemic Stroke after General ...

ABSTRACT: Background and Objective: The peri-anaesthetic management of an elderly patient is significantly different from that of a young patient. This study was conducted to determine the morbidity ...
BMJ

POS1422 ASSOCIATION BETWEEN ANTIBIOTIC USE AND THE ONSET OF GIANT CELL ARTERITIS AND POLYMYALGIA RHEUMATICA: A NESTED CASE CONTROL STUDY FROM THE ...

1 Universite Paris-Saclay, UVSQ, Inserm, CESP, 94807, Villejuif, France 2 Universite Paris-Saclay, UVSQ, Inserm, CESP, Villejuif, France 3 Université Paris-Saclay ...
ascopubs.org

Performance of Two-Phase Designs for the Time-to-Event Outcome and a Case Study Assessing the Relapse Risk Associated With B-ALL Subtypes

As biomarker studies employ increasingly complex and expensive genomics and other correlative methods, it is increasingly important to rigorously design these studies and analyze the downstream ...