Decoding Pyrexia of Unknown Origin (PUO)! A patient with fever for >3 weeks, multiple negative investigations, and failed antibiotic courses. It's a classic PUO case. 🧩 The Golden Dictum: "PUO is more likely a Common Disease presenting Atypically, rather than a Rare Disease presenting Typically." 🔍 The Big 4 Categories to Investigate: Infections: Still the #1 cause (TB, Endocarditis, Abscesses). Note: As duration increases, likelihood of infection decreases. Malignancy: Lymphomas, Leukemia, RC
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Decoding Pyrexia of Unknown Origin (PUO)! A patient with fever …
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Pyrexia - Confrontation
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PYREXIA OF UNKNOWN ORIGIN - SlideServe
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Pyrexia is any temperature over 38.2 (100.7F) but there are two types of pyrexia. Intrinsic is induced by your immune system - typically white blood cells called Macrophages that produce pyrogens (heat stimulating chemicals ) instructing your brains thermostat to raise. These intrinsic pyrexia are simply called FEVER and are most commonly triggered by infection. Extrinsic Pyrexia is called Hyperthermia and triggered by an outside influence like heat, or certain medications (Serotonergic, Dopamin
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