Tryptase? I check it, sure. But I can’t say I care when it’s negative. Tryptase is elevated in only a minority of those with mast cell activation. That’s why the new Consensus-2 guidelines updated the diagnostic framework for MCAS — and finally gave us the flexibility to treat the patient, not just the numbers. Consensus-2 Criteria for MCAS: 1. Typical symptoms of mast cell activation (affecting ≥2 systems — e.g., flushing, GI upset, tachycardia, brain fog) 2. Elevated mast cell mediators (e.g.,

Testing for MCAS? You need to measure histamine, tryptase, leukotrienes, but results vary daily—tests must be done during a flare, and not all doctors offer them. #MCAS #MastCellActivation #FunctionalMedicine #HealthTips #DrKan | Hope Integrative Wellness Center